M. Legrelle et al., LIPOPROTEIN(A) AND CARDIOVASCULAR RISK-FA CTORS - A STUDY IN 131 PATIENTS WITH DIABETES-MELLITUS, La Semaine des hopitaux de Paris, 70(7-8), 1994, pp. 191-197
This cross-sectional study evaluated the distribution of Lp(a) levels
in 131 diabetics and 182 controls and looked for correlations between
Lp(a) levels and occurrence of degenerative complications of diabetes
mellitus. Lp(a) levels were lower in patients with Type 1diabetes mell
itus than in non-insulin-dependent diabetics or controls. Among patien
ts with Type II diabetes mellitus, females had higher Lp(a) levels. Pl
asma Lp(a) levels were significantly correlated with fructosamine leve
ls. Among patients with Type 2 diabetes mellitus, a weak but significa
nt correlation was found between Lp(a) levels and presence of macroang
iopathy. However, Lp(a) levels were not significantly correlated with
microalbuminuria or diabetic retinopathy.