EFFECTS OF PIMOBENDAN ON ISOLATED HUMAN RIGHT ATRIA STRIPS AND ON ISOLATED LEFT ATRIA OF THE RAT

Authors
LLOBELL F DAVALOS R LAORDEN ML
Citation
F. Llobell et al., EFFECTS OF PIMOBENDAN ON ISOLATED HUMAN RIGHT ATRIA STRIPS AND ON ISOLATED LEFT ATRIA OF THE RAT, European journal of anaesthesiology, 11(2), 1994, pp. 123-125
Citations number
NO
Categorie Soggetti
Anesthesiology
Journal title
European journal of anaesthesiology → ACNP
ISSN journal
02650215
Volume
11
Issue
2
Year of publication
1994
Pages
123 - 125
Database
ISI
SICI code
0265-0215(1994)11:2<123:EOPOIH>2.0.ZU;2-7
Abstract
The present study describes the effects of pimobendan on isolated huma n right atrial strips and on isolated left atria of the rat. Pimobenda n induces a positive inotropic effect both in human and rat preparatio ns. The maximal increase (28 +/- 2.0%) obtained with pimobendan in the strips from human right atria was similar to that obtained In left at ria of the rat (31 +/- 1.8%). These observations may have some clinica l relevance as pimobendan might prove to be an alternative to catechol amines for inotropic support in patients who undergo general anaesthes ia.