F. Llobell et al., EFFECTS OF PIMOBENDAN ON ISOLATED HUMAN RIGHT ATRIA STRIPS AND ON ISOLATED LEFT ATRIA OF THE RAT, European journal of anaesthesiology, 11(2), 1994, pp. 123-125
The present study describes the effects of pimobendan on isolated huma
n right atrial strips and on isolated left atria of the rat. Pimobenda
n induces a positive inotropic effect both in human and rat preparatio
ns. The maximal increase (28 +/- 2.0%) obtained with pimobendan in the
strips from human right atria was similar to that obtained In left at
ria of the rat (31 +/- 1.8%). These observations may have some clinica
l relevance as pimobendan might prove to be an alternative to catechol
amines for inotropic support in patients who undergo general anaesthes
ia.