V. Rohlicek et J. Rohlicek, MEASUREMENT OF MEMBRANE CAPACITANCE AND RESISTANCE OF SINGLE CELLS USING 2 FREQUENCIES, Physiological Research, 42(6), 1993, pp. 423-428
A method for the measurement of the membrane capacitance and resistanc
e with two simultaneous sinusoidal frequencies is described. This meth
od combines the advantages of measurements with a single sinusoidal fr
equency (i.e. low noise - high resolution) and those with rectangular
waveform or polyfrequent methods. The mathematical analysis of the imp
edance as well as the admittance are presented for the evaluation with
synchronous detection. Preliminary results are given.