A NOVEL CHROMOSOMAL ABNORMALITY DETECTED IN A CASE OF ACUTE MYELOMONOCYTIC LEUKEMIA

Authors
FIORILLO A SEBASTIO L DELVECCHIO L MIGLIORATI R DECHIARA C DAMORE R VICARI L PASTORE A SELLERI C
Citation
A. Fiorillo et al., A NOVEL CHROMOSOMAL ABNORMALITY DETECTED IN A CASE OF ACUTE MYELOMONOCYTIC LEUKEMIA, Leukemia, 8(2), 1994, pp. 309-311
Citations number
6
Categorie Soggetti
Hematology,Oncology
Journal title
Leukemia → ACNP
ISSN journal
08876924
Volume
8
Issue
2
Year of publication
1994
Pages
309 - 311
Database
ISI
SICI code
0887-6924(1994)8:2<309:ANCADI>2.0.ZU;2-O
Abstract
A not yet recorded translocation, t(3;17)(q21;q23), detected in a case of acute myelomonocytic leukemia, is reported. In spite of an aggress ive cytotoxic chemotherapy, the disease showed a rapid fatal course, c onfirming the dismal prognostic significance of structural, 'primary' chromosomal abnormalities in acute leukemias.