Ocean Drilling Program observations at many accretionary wedges indica
te that fluid flow in low-permeability sediments is focused along faul
ts rich in clay minerals. Recent ring-shear experiments show that shea
r failure generally reduces permeability in muddy faults to values wel
l below the surrounding sediments and that very little increase occurs
in the fault permeability even when continued failure proceeds under
steadily reduced effective loads. It is, thus, unlikely that observed
focused flow occurs through the matrix of muddy faults, and we suggest
that focused flow can only be explained by the development of open fr
acture systems. The lithostatic fluid pressures necessary for hydrofra
cturing in weak sediments cannot, however, exist throughout the imbric
ate thrust system and basal decollement zone because a zero basal shea
r stress condition would result in regional instability and accretiona
ry wedge collapse. We propose that the regional hydrofracture networks
must propagate heterogeneously, leaving relatively strong asperity re
gions at sublithostatic fluid pressures to balance forces in the wedge
in three dimensions.