Z. Genovefa et al., IMPROVEMENT OF LIPASE PRODUCTION BY ADDITION OF CATALASE DURING FERMENTATION, Applied microbiology and biotechnology, 40(5), 1994, pp. 650-652
A batch fermentation process for lipase production with the recombinan
t strain Staphylococcus carnosus (pLipMut2) was studied in a bubble co
lumn. The rates of growth and lipase production in this type of fermen
ter were compared with results from shake-flasks. It was seen that cul
tivation in the bubble column resulted in a prolonged lag time and a r
educed lipase activity in comparison to flask cultures. However, by ad
dition of catalase during the fermentation in the bubble column this d
ifferent behaviour could be avoided.