A novel membrane bioreactor, previously assessed for its gas transfer
characteristics, was used in various size and membrane configurations
for the growth of the strictly aerobic bacterium Pseudomonas aeruginos
a. The bioreactor was found to readily support growth, and the initial
growth rates showed the previously demonstrated enhanced effect in ga
s O-2 mass transfer of the dimpled membrane bioreactor over flat membr
ane bioreactors. The production of a secondary metabolite by a Pseudom
onas sp. following growth was demonstrated, as was the biotransformati
on of a nitrile by nocardia rhodochrous with the removal of the biotra
nsformation products across a membrane. The potential of the bioreacto
r, in terms of other applications in the field of biotechnology, is di
scussed.