Stereotactic localization and fine-needle aspiration are new procedure
s for the management of non-palpable mammographic abnormalities. In th
is prospective study, stereo-tactically guided cytology with immediate
reporting was performed before biopsy in a consecutive series of 166
patients with screen-detected non-palpable abnormalities. All specimen
s were obtained by multiple stereotactically guided passes with a 22-G
Franzen needle and graded as: 1, acellular or inadequate; 2, benign;
3, atypical, probably benign; 4, probably malignant; or 5, malignant.
After definitive surgery all tumours were staged according to the Unio
n Internacional Contra la Cancrum classification. Of 71 patients with
malignancy, 56 were correctly diagnosed by cytology before operation.
Twelve patients with malignancy had grade 1 cytology and 50 of the 52
with grade 2 cytology had benign disease. This study confirms that ste
reotactic cytology is a valuable diagnostic test in a breast-screening
programme.