The presentation, oesophageal profile and management of 27 symptomatic
patients with daytime (upright) gastrooesophageal reflux only is repo
rted. Oesophagitis was a presenting feature in 11 patients and its dev
elopment was most closely correlated with postprandial reflux, which w
as characterized by cumulative acid exposure rather than by clearance
abnormalities. Upright reflux was not associated with a hypotensive lo
wer oesophageal sphincter or with oesophageal dysmotility. Antireflux
surgery is indicated when conservative measures fail and was not assoc
iated with gas-bloat syndrome after operation.