NATIVE VALVE ENDOCARDITIS DUE TO CANDIDA-PARAPSILOSIS - A LATE COMPLICATION AFTER BONE-MARROW TRANSPLANTATION-RELATED FUNGEMIA

Authors
CANCELAS JA LOPEZ J CABEZUDO E NAVAS E LARANA JG MENA MJ DIZ P DEOTEYZA JP VILLALON L SANCHEZSOUSA A SASTRE JL ODRIOZOLA J NAVARRO JL
Citation
Ja. Cancelas et al., NATIVE VALVE ENDOCARDITIS DUE TO CANDIDA-PARAPSILOSIS - A LATE COMPLICATION AFTER BONE-MARROW TRANSPLANTATION-RELATED FUNGEMIA, Bone marrow transplantation, 13(3), 1994, pp. 333-334
Citations number
10
Categorie Soggetti
Hematology,Oncology,Immunology
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
13
Issue
3
Year of publication
1994
Pages
333 - 334
Database
ISI
SICI code
0268-3369(1994)13:3<333:NVEDTC>2.0.ZU;2-G
Abstract
A case of Candida parapsilosis endocarditis observed 16 months after B MT is reported. The patient, a 35-year-old female with CML, suffered f rom Candida parapsilosis fungemia on day +22 after BMT. In spite of tr eatment with amphotericin B, fluconazole and catheter withdrawal, the same yeast was isolated > 1 year later from a vegetation on an old rhe umatic mitral valve. Although the patient remained in complete cytogen etical and hematological remission, in vitro tests showed reduced phag ocytic and chemotactic capacity of neutrophils and monocytes. This cas e stresses the need of prolonged therapy for patients with candidemia after BMT.