TREATMENT OF LUPUS INTERSTITIAL LUNG-DISEASE WITH INTRAVENOUS CYCLOPHOSPHAMIDE

Authors
EISER AR SHANIES HM
Citation
Ar. Eiser et Hm. Shanies, TREATMENT OF LUPUS INTERSTITIAL LUNG-DISEASE WITH INTRAVENOUS CYCLOPHOSPHAMIDE, Arthritis and rheumatism, 37(3), 1994, pp. 428-431
Citations number
25
Categorie Soggetti
Rheumatology
Journal title
Arthritis and rheumatism → ACNP
ISSN journal
00043591
Volume
37
Issue
3
Year of publication
1994
Pages
428 - 431
Database
ISI
SICI code
0004-3591(1994)37:3<428:TOLILW>2.0.ZU;2-2
Abstract
Intravenous pulse cyclophosphamide (IPC) was used to treat lupus inter stitial lung disease in 2 patients. Vital capacity increased by 67-110 % of baseline values with IPC treatment. Total lung capacity and diffu sing capacity also improved. Dyspnea and other manifestations of lupus improved dramatically. This is the first report documenting the effic acy of the early use of IPC for acute and chronic interstitial lung di sease associated with lupus.