VILSMEIER-HAACK REAGENT - A FACILE SYNTHESIS OF 4-HETEROMETHYLENE-2-ARYL-2-OXAZOLIN-5-ONES FROM N-ACYL-ALPHA-AMINO ACID-ESTERS

Authors
Citation
Kk. Singh et Rm. Singh, VILSMEIER-HAACK REAGENT - A FACILE SYNTHESIS OF 4-HETEROMETHYLENE-2-ARYL-2-OXAZOLIN-5-ONES FROM N-ACYL-ALPHA-AMINO ACID-ESTERS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(3), 1994, pp. 232-235
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
03764699
Volume
33
Issue
3
Year of publication
1994
Pages
232 - 235
Database
ISI
SICI code
0376-4699(1994)33:3<232:VR-AFS>2.0.ZU;2-U
Abstract
N-dimethylaminomethylene)-2-aryl-2-oxazolin-5-ones (5) have been synth esised from N-acyl-alpha-amino acid esters (3) by treating with Vilsme ier-Haack reagent, in good yield. The variable temperature-NMR study a nd a plausible mechanism have also been discussed.