Kk. Singh et Rm. Singh, VILSMEIER-HAACK REAGENT - A FACILE SYNTHESIS OF 4-HETEROMETHYLENE-2-ARYL-2-OXAZOLIN-5-ONES FROM N-ACYL-ALPHA-AMINO ACID-ESTERS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(3), 1994, pp. 232-235
N-dimethylaminomethylene)-2-aryl-2-oxazolin-5-ones (5) have been synth
esised from N-acyl-alpha-amino acid esters (3) by treating with Vilsme
ier-Haack reagent, in good yield. The variable temperature-NMR study a
nd a plausible mechanism have also been discussed.