VILSMEIER-HAACK REACTION OF AZASTEROIDS

Authors
RANJU,"PATHAK D JINDAL DP
Citation
D. Ranju,"pathak et Dp. Jindal, VILSMEIER-HAACK REACTION OF AZASTEROIDS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(3), 1994, pp. 269-271
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
33
Issue
3
Year of publication
1994
Pages
269 - 271
Database
ISI
SICI code
0376-4699(1994)33:3<269:VROA>2.0.ZU;2-E
Abstract
17Beta-acetoxy-4-aza-5alpha-androstan-3-one (1) land 3beta-acetoxy-17- aza-D-homoandrost-5-en-17-one on Vilsmeier-Haack formylation reaction give toxy-3-chloro-4-aza-5alpha-androst-2-en-2-aldehyde (2) and 3beta- acetoxy-17-chloro-17a -aza-D-homoandrost-5, 16-dien-16-aldehyde (4), r espectively. The aldehydes 2 and 4 on treatment with methanolic KOH af ford oxy-3-methoxy-4-aza-5alpha-androst-2-en-2-aldehyde (3) and 3beta- hydroxy-17-methoxy-17a-aza-D-homoandrost-5, 16-dien-16-aldehyde (5), r espectively.