INCOMPLETE EXCISION OF CIN IN CONIZATION - FURTHER EXCISION OR CONSERVATIVE MANAGEMENT

The aim of this study was to investigate the experience of the further management in 112 cases with histological diagnosis of incomplete exc ision of CIN in cone biopsy. Two groups of women were studied. The wom en in the first group (n = 78) had a second excision while the women i n the second group (n = 34) underwent conservative management with cyt ology and colposcopy. The histologic, cytologic and colposcopic findin gs in the women of both groups were compared. From the first group 38% had a second cone, 62% an hysterectomy; in 5 cases the second cone wa s followed by hysterectomy and the histology was negative in 75% and 6 5%, respectively. No indication of residual disease was found within 2 -10 years of follow-up in any of the women in the second group. Accord ing to our study and being aware of the natural history of CIN, we can conclude that the decision for further excision should not be based e xclusively on the histology report of involved margins, but should onl y be taken after careful cytological and colposcopic selection of the cases.