SYNTHESIS OF THE VARIAMINE BLUE B-BASE

The paper presents a systematic study of the steps encountered in the synthesis of the variamine base. The optimum conditions of obtaining t he intermediate have been established, resulting in improved end-produ ct yields. The experimental work led to significant modifications of t he reaction parameters in the reduction step. This allowed for the dim inishing of the reaction time and improving the end-product yield afte r the first two process steps. The difficulties mentioned in the liter ature, concerning the removal of the sulfonic group, have been surpass ed there thus achieving a rigorous desulfonation control.