REGIOSPECIFICITY IN THE CYCLIZATION OF 6-(1-HYDROXYALKYL) GERANIOL DERIVATIVES - A SIMPLE ROUTE TO THE TAXOL A-RING SYSTEM

Authors
DOI T ROBERTSON J STORK G YAMASHITA A
Citation
T. Doi et al., REGIOSPECIFICITY IN THE CYCLIZATION OF 6-(1-HYDROXYALKYL) GERANIOL DERIVATIVES - A SIMPLE ROUTE TO THE TAXOL A-RING SYSTEM, Tetrahedron letters, 35(10), 1994, pp. 1481-1484
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
10
Year of publication
1994
Pages
1481 - 1484
Database
ISI
SICI code
0040-4039(1994)35:10<1481:RITCO6>2.0.ZU;2-4
Abstract
Readily available derivatives of geraniol bearing a 1-hydroxyalkyl sid e chain in the 6-position undergo acid-catalyzed regiospecific cycliza tion to form cyclogeraniol derivatives which have an interesting relat ion to ring A of taxol.