ALLERGIC VASCULITIS DUE TO GAMMA-VINYL GA BA TREATMENT

A patient with focal epilepsy that was resistant to medical treatment received add-on therapy with vigabatrin. Six months after commencement of vigabatrin therapy, allergic vasculitis caused by vigabatrin was d iagnosed. The patient displayed unilateral anterior ischaemic optic ne uropathy with impairment of vision and concentric loss of visual field . The diagnosis was based on the lymphocyte transformation test and th e clinical course. The allergic vasculitis was healed by cortisone the rapy.