COMPARISON OF THE MAXIMUM SENSITIVITY OF DIFFERENT FLOW-INJECTION MANIFOLD CONFIGURATIONS - ALTERNATING VARIABLE SEARCH OPTIMIZATION OF THEIRON(II) 1,10-PHENANTHROLINE SYSTEM/

Three manifold configurations used in flow injection analysis were opt imized for maximum sensitivity for the spectrophotometric determinatio n of iron(II) by complexation with 1,10-phenanthroline. The parameters of flow rate(s), injected volume, manifold length, and reagent concen tration were studied for single, double, and reverse single line now i njection manifolds. All the manifolds produced maximum sensitivity whe n the dispersion coefficient (measured from the product profile) was l ess than 1.1. All the flow injection configurations were of comparable sensitivity, with that of the reverse configuration being slightly hi gher than those of the other two. The double line configuration gave t he lowest detection limit(10 ng mL(-1)) because of the absence of refr active index peaks.