MOSQUITO REPELLENCY AND TOXICITY OF ISOMERIC N,N-DIETHYLTOLYLACETAMIDES

Authors
SIKDER N GOPALAN N PRAKASH S VINOD VK RAO SS RAO KM
Citation
N. Sikder et al., MOSQUITO REPELLENCY AND TOXICITY OF ISOMERIC N,N-DIETHYLTOLYLACETAMIDES, INDIAN JOURNAL OF MEDICAL RESEARCH, 99, 1994, pp. 121-123
Citations number
12
Categorie Soggetti
Medicine, General & Internal",Immunology
Journal title
INDIAN JOURNAL OF MEDICAL RESEARCH → ACNP
ISSN journal
09715916
Volume
99
Year of publication
1994
Pages
121 - 123
Database
ISI
SICI code
0971-5916(1994)99:<121:MRATOI>2.0.ZU;2-P
Abstract
Three isomers of N, N-diethyltolylacetamides were synthesized and eval uated against Aedes aegypti and Culex quinquefasciatus for repellency and with mice for LD50, as an indicator of mammalian toxicity. Of thes e, N, N-diethyl-p-tolylacetamide (DEPTA) showed comparatively better r epellency against C. quinquefasciatus. All the compounds showed higher repellency against C. quinquefasciatus than Ae. aegypti. In addition, N, N-diethyl-m-tolylacetamide (DEMTA) was found to be least toxic to mice.