EFFECTS OF CYCLOSPORINE-A ON HAIR

Cyclosporin A (CSA) is an immunosuppressive agent that has provided ne w approaches in transplantation medicine and in the treatment of autoi mmune diseases. One of the most common dermatological side effects of oral CSA is dose-dependent hypertrichosis. This stimulating effect on hair growth encouraged a number of investigators to use CSA not only i n the treatment of alopecia areata (AA), but also in male pattern alop ecia (MPA). While oral application proved successful, the beneficial e ffect of topical application was very limited in both AA and MPA.