E. Schonau et al., THE DETERMINATION OF ULTRASOUND VELOCITY IN THE OS CALCIS, THUMB AND PATELLA DURING CHILDHOOD, European journal of pediatrics, 153(4), 1994, pp. 252-256
Maximising the accumulation of bone tissue during growth and puberty i
s one of the most important aims in the prevention of osteoporosis. Fo
r prevention studies in children it is necessary to develop methods fo
r skeletal status without radiation. Ultrasonic velocity (speed of sou
nd = SOS) has been proposed as an alternative method. Using a new ultr
asonic system (Osteoson K4, Minhorst, Germany), we investigated the re
producibility and age-dependency of SOS in several peripheral bones in
218 children and young adults. Intra-observer (day to day) reproducib
ility: calcaneus CV = 0.64%, patella CV = 1.18% and thumb CV = 0.43% (
n = 25). Inter-observer reproducibility: calcaneus CV = 1.1%, patella
CV = 2.48% and thumb CV = 0.62% (n = 16). SOS in thumb and patella inc
reased with age and peaked at 20-25 years. SOS in the calcaneus showed
no increase after puberty. Studies in bones from pigs show no depende
ncy of SOS from the thickness of analysed cortical or trabecular bone
slices. We conclude that the reproducibility of SOS measurements espec
ially in the thumb is comparable with those of radiation methods. The
SOS data in growing, healthy children and the independency from bone d
imensions provides more evidence that SOS describes the elastic qualit
ies of the bones.