Jr. Jindal et al., GASTROESOPHAGEAL REFLUX DISEASE AS A LIKELY CAUSE OF IDIOPATHIC SUBGLOTTIC STENOSIS, The Annals of otology, rhinology & laryngology, 103(3), 1994, pp. 186-191
The cause of subglottic stenosis (SGS) is unknown for a subgroup of pa
tients in which there is a female predominance. Seven women ranging in
age from 39 to 66 years developed symptomatic and progressive SGS. Si
x of the 7 patients failed to respond to all measures of conservative
and radical surgical intervention. After recent thorough evaluation fo
r gastroesophageal reflux disease (GERD) followed by medical managemen
t for such, these 6 patients have stabilized and have responded to sur
gical management. The seventh patient recently presented with SGS, was
evaluated and treated for GERD, and has not required any surgical man
agement. This study suggests that GERD laryngitis may be pertinent in
the development of SGS. Medical management of GERD thus appears vital
to successful treatment of idiopathic SGS.