SALIVARY DUCT CARCINOMA

Salivary duct carcinoma is a high-grade neoplasm associated primarily with the parotid gland. Its abysmal prognosis demands aggressive clini cal management. Initially named after its resemblance to intraductal c arcinoma of the breast, this entity derives its histogenesis from the excretory duct reserve cells, which are also the source of origin of o ther biologically high-grade neoplasms. As this is a lesion seldom enc ountered by the clinician, it is important for the pathologist to clea rly make the distinction between this malignancy and more indolent neo plasms, such as terminal duct adenocarcinoma