HORIZONTAL OR VERTICAL 50-HZ, 1-MU-T MAGNETIC-FIELDS HAVE NO EFFECT ON PINEAL-GLAND OR PLASMA MELATONIN CONCENTRATION OF ALBINO-RATS

Three experiments were carried out on male Wistar-King rats to determi ne if 6 weeks of exposure to horizontally- or vertically- oriented 1-m u T, 50-Hz magnetic fields suppresses melatonin content in plasma and pineal gland, as does 6 weeks of exposure to circularly-polarized, 50- Hz, 1-mu T magnetic fields. In each experiment, a concurrent sham-expo sed control group was exposed to a stray field of 0.02 mu T. In additi on, a separate control experiment was completed between the horizontal and vertical held experiments in which cage-controls were housed in t he exposure facility for 6 weeks without activation of the magnetic fi eld coils. Subjects were sacrificed at 12:00 or at 24:00 h for collect ion of plasma and pineal gland; melatonin was determined by radioimmun oassay. In contrast to the results of experiments with rotating-vector magnetic fields, there were no significant differences among 1-mu T, 0.02-mu T and control groups in melatonin concentration of pineal glan d or plasma.