Intraaortic balloon pump support has been demonstrated to be of clinic
al benefit when used therapeutically and prophylactically in high-risk
patients undergoing percutaneous transluminal coronary angioplasty (P
TCA). Afterload reduction and post-PTCA-enhanced coronary blood flow a
fforded by diastolic augmentation during intraaortic balloon pumping p
rovides hemodynamic stabilization, attenuates clinical perturbations o
f myocardial ischemia, and may provide an important 'bridge' to emerge
nt coronary bypass surgery following abrupt vessel closure complicatin
g PTCA. Recent studies demonstrate a reduction in cardiac morbidity an
d improved coronary artery patency among patients receiving prophylact
ic intraaortic balloon pumping after establishing infarct artery reper
fusion during acute cardiac catheterization for acute myocardial infar
ction. A modest increase in cardiac output (20-30%), the requirement o
f a stable, regular cardiac rhythm, peripheral vascular disease and ao
rtic insufficiency limits the use of intraaortic balloon pump support
in relatively few patients. These studies demonstrate that intraaortic
balloon counterpulsation provides an effective and safe form of mecha
nical support in many high-risk patients undergoing PTCA.