TENASCIN - DOES IT PLAY A ROLE IN EPIDERMAL MORPHOGENESIS AND HOMEOSTASIS

Authors
LIGHTNER VA
Citation
Va. Lightner, TENASCIN - DOES IT PLAY A ROLE IN EPIDERMAL MORPHOGENESIS AND HOMEOSTASIS, Journal of investigative dermatology, 102(3), 1994, pp. 273-277
Citations number
59
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Journal of investigative dermatology → ACNP
ISSN journal
0022202X
Volume
102
Issue
3
Year of publication
1994
Pages
273 - 277
Database
ISI
SICI code
0022-202X(1994)102:3<273:T-DIPA>2.0.ZU;2-T
Abstract
Tenascin is a large glycoprotein of the extracellular matrix. its comp lex multidomain structure, along with its unique distribution during e mbryogenesis, inflammation, wound healing, and tumorgenesis suggest th is protein may play a significant role in regulating cell proliferatio n, migration, and differentiation. In this review I will summarize the structural features of tenascin an its localization in s n an discuss some of the potential roles of tenascin in the regulation of keratino cyte biology.