Our study of the different biomaterials used in the construction of bi
ological cardiac prostheses has shown it to be of vital importance tha
t the physical properties of the tissue and of the suture that anchors
it to the rigid polymeric support are compatible. By means of dynamic
tests, we have determined the fatigue curve in sutured bovine pericar
dial tissue, expressed by the equation log y = 1.27 +/- 0.18 - (0.26 /- 0.05) log t, where y is the initial fatigue stress (MPa) and t is t
he time (min) it takes to achieve permanent deformation of the tissue.
By applying this correction, we determine a set of values for stress-
time which, when compared with those obtained with a non-sutured sampl
e, reveal a significant fall in this ratio and, thus, a decrease in th
e durability. The use of suture threads of lesser elasticity than the
pericardium may play an important role in reducing the durability of t
he bioprosthesis constructed with these materials.