LOBULAR CARCINOMA OF THE MALE BREAST

Background. A case of lobular carcinoma in a male breast is described. Lobular carcinoma is a very uncommon histopathologic form of male bre ast cancer because of the absence of lobules in the normal male breast . The cytoarchitecture of the normal male breast can be deranged in co nditions such as Klinefelter's syndrome or as a result of estrogen exp osure. Lobular carcinoma of the male breast has been described in such instances where cytoarchitectural changes are likely to have occurred . Methods and Results. After the pathologic diagnosis was made, a fibr oblast karyotype was performed to confirm a male genotype. The patient had received no hormonal therapy. The English language literature was reviewed. Conclusion. This case represents the first report of lobula r carcinoma in a proven genotypic male patient receiving no exogenous estrogens.