LIPASE-CATALYZED SYNTHESIS OF OLEIC-ACID ESTERS OF POLYETHYLENE-GLYCOL-400

Authors
JANSSEN GG HAAS MJ
Citation
Gg. Janssen et Mj. Haas, LIPASE-CATALYZED SYNTHESIS OF OLEIC-ACID ESTERS OF POLYETHYLENE-GLYCOL-400, Biotechnology letters, 16(2), 1994, pp. 163-168
Citations number
16
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
2
Year of publication
1994
Pages
163 - 168
Database
ISI
SICI code
0141-5492(1994)16:2<163:LSOOEO>2.0.ZU;2-8
Abstract
Quantitative esterification of polyethylene glycol (PEG) 400 using ole ic acid and Lipozyme was achieved in hexane. The effects of temperatur e, nature of acyl donor, substrate ratio, enzyme quantity and reaction time upon PEG esterification were examined. Nearly selective producti on of either PEG monooleate or PEG dioleate was achieved. Lipozyme was still 80% active after five reaction cycles.