PHARMACOLOGICAL STIMULATION OF SPERM MOTILITY

The treatment of male factor infertility is a rapidly developing field . The introduction of microsurgical fertilization techniques allows as sisted conception units to treat couples who previously would not have benefited from in-vitro fertilization techniques. However, these tech niques are only used for the minority of subfertile men in andrologica l practice. Many subfertile men are still treated pharmacologically or by sperm selection methods to enhance sperm fertilizing ability. Nume rous pharmacological compounds have been described that enhance sperm motility and thus, potentially, sperm fertilizing capacity. This paper attempts to review these compounds and assess their role in treatment of the subfertile male.