ASSESSMENT OF THE CONVENTIONAL CRITERIA OF SEMEN QUALITY BY COMPUTER-ASSISTED IMAGE-ANALYSIS - EVALUATION OF THE HAMILTON-THORN MOTILITY ANALYZER IN THE CONTEXT OF A SERVICE ANDROLOGY LABORATORY
Ic. Macleod et al., ASSESSMENT OF THE CONVENTIONAL CRITERIA OF SEMEN QUALITY BY COMPUTER-ASSISTED IMAGE-ANALYSIS - EVALUATION OF THE HAMILTON-THORN MOTILITY ANALYZER IN THE CONTEXT OF A SERVICE ANDROLOGY LABORATORY, Human reproduction, 9(2), 1994, pp. 310-319
A comparative assessment of the conventional criteria of semen quality
(sperm concentration, motility and morphology) was undertaken by stan
dard laboratory techniques and by means of a computer-assisted image a
nalysis system (the Hamilton - Thorn HTM-S 2030) in an open prospectiv
e study, in the context of a service andrology laboratory. A total of
1435 semen samples submitted by couples in the course of routine infer
tility investigations were examined by both methods, and the results c
ompared. It was observed that the method did not provide comparable da
ta on semen quality, either in respect of sperm concentration or grade
d motility, while the morphometric data generated by the HTM-S did not
appear to be related to conventional morphology assessment. The clini
cal value of such systems in the assessment of the classical determina
nts of semen quality requires formal assessment in properly conducted
large scale prospective studies.