Objective: To assess the anatomic outcome and visual acuities at follo
w-up after pars plana vitrectomy in the management of stage 2 macular
holes. Design: Retrospective. Setting: Retina Consultants, Ltd, St Lou
is, Mo. Patients: Thirty-three patients, aged 43 to 75 years, with sta
ge 2 macular holes. Intervention: Total pars plana vitrectomy with sep
aration of the posterior hyaloid membrane and injection of intraocular
gas followed by postoperative facedown positioning. Main Outcome Meas
ures: Visual acuity and anatomic appearance of the macular hole. Resul
t: Postoperatively, 20 (61%) of 33 eyes attained a visual acuity of 20
/50 or greater. Twenty (61%) of 33 eyes showed an improvement in visua
l acuity, while nine (27%) of 33 were stable. Four (12%) of 33 eyes sh
owed a decline in postoperative visual acuity with progression to a st
age 3 macular hole. Twenty-five (76%) of 33 eyes showed stabilization
or improvement in the appearance of the macular hole. Conclusions: Par
s plana vitrectomy in conjunction with postoperative intraocular gas t
amponade may result in visual and anatomic stabilization or improvemen
t in eyes with stage 2 macular holes. However, because of limited natu
ral history data, it is unknown whether these results are any better t
han those that might occur without surgery.