INTRACELLULAR CALCIUM SIGNALS ARE ENHANCED FOR DAYS AFTER PAVLOVIAN CONDITIONING

Citation
E. Ito et al., INTRACELLULAR CALCIUM SIGNALS ARE ENHANCED FOR DAYS AFTER PAVLOVIAN CONDITIONING, Journal of neurochemistry, 62(4), 1994, pp. 1337-1344
Citations number
30
Categorie Soggetti
Biology,Neurosciences
Journal title
ISSN journal
00223042
Volume
62
Issue
4
Year of publication
1994
Pages
1337 - 1344
Database
ISI
SICI code
0022-3042(1994)62:4<1337:ICSAEF>2.0.ZU;2-4
Abstract
Previous observations have implicated GABA as a neurotransmitter relea sed by the vestibular sensory neurons (''hair cells'') of the snail He rmissenda onto visual sensory neurons, the type B cells, whose cell bo dies are the sites of biophysical and biochemical changes during and f ollowing Pavlovian conditioning. Still other observations demonstrated that light-GABA pairings that simulate stimuli presented during Pavlo vian conditioning cause prolonged elevation of intracellular Ca2+ and transformation of GABA-induced synaptic inhibition into excitation. In tracellular Ca2+ signals in response to GABA perfused onto the postsyn aptic type B terminal branches are shown here to be prolonged on days after conditioning, but not after control paradigms. These and past re sults demonstrate two separate sites, i.e., the cell body and the term inal branches, for learning-induced changes after Pavlovian conditioni ng.