A PROCEDURE FOR THE PREPARATION OF CARDIOACTIVE STEROID PRECURSORS - SYNTHESIS OF BETA-ACETOXY-21-HYDROXY-5-ALPHA-PREGN-14-EN-20-ONE

Authors
SIMBI L VANHEERDEN FR
Citation
L. Simbi et Fr. Vanheerden, A PROCEDURE FOR THE PREPARATION OF CARDIOACTIVE STEROID PRECURSORS - SYNTHESIS OF BETA-ACETOXY-21-HYDROXY-5-ALPHA-PREGN-14-EN-20-ONE, Journal of the Chemical Society. Perkin transactions. I, (3), 1997, pp. 269-273
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
3
Year of publication
1997
Pages
269 - 273
Database
ISI
SICI code
0300-922X(1997):3<269:APFTPO>2.0.ZU;2-L
Abstract
The efficient preparation of an important precursor in the synthesis o f cardioactive steroids is reported. The key step, the introduction of a 21-hydroxy group into a 14,15-dehydropregnane derivative, is accomp lished by reaction of the enol ether with dimethyldioxirane.