HEAT-CONDUCTION CALORIMETERS - TIME CONSTANTS, SENSITIVITY AND FAST TITRATION EXPERIMENTS

Authors
BACKMAN P BASTOS M HALLEN D LONNBRO P WADSO I
Citation
P. Backman et al., HEAT-CONDUCTION CALORIMETERS - TIME CONSTANTS, SENSITIVITY AND FAST TITRATION EXPERIMENTS, Journal of biochemical and biophysical methods, 28(2), 1994, pp. 85-100
Citations number
16
Categorie Soggetti
Biology,Biophysics,"Biochemical Research Methods
Journal title
Journal of biochemical and biophysical methods → ACNP
ISSN journal
0165022X
Volume
28
Issue
2
Year of publication
1994
Pages
85 - 100
Database
ISI
SICI code
0165-022X(1994)28:2<85:HC-TCS>2.0.ZU;2-0
Abstract
Seven heat conduction calorimeters have been evaluated in terms of sen sitivity and thermal response time. The use of a dynamic method to cor rect for the thermal inertia of the calorimeter is shown to reduce by one order of magnitude the time required to conduct a stepwise titrati on experiment involving a fast reaction. The ability to determine asso ciation constants of strong 1:1 complexes has been evaluated in terms of the precision of determining thermal energy.