IDENTIFICATION OF A NOVEL SUGAR, 4-AMINO-4,6-DIDEOXY-2-O-METHYLMANNOSE IN THE LIPOPOLYSACCHARIDE OF VIBRIO-CHOLERAE O1 SEROTYPE OGAWA

Authors
ITO T HIGUCHI T HIROBE M HIRAMATSU K YOKOTA T
Citation
T. Ito et al., IDENTIFICATION OF A NOVEL SUGAR, 4-AMINO-4,6-DIDEOXY-2-O-METHYLMANNOSE IN THE LIPOPOLYSACCHARIDE OF VIBRIO-CHOLERAE O1 SEROTYPE OGAWA, Carbohydrate research, 256(1), 1994, pp. 113-128
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Carbohydrate research → ACNP
ISSN journal
00086215
Volume
256
Issue
1
Year of publication
1994
Pages
113 - 128
Database
ISI
SICI code
0008-6215(1994)256:1<113:IOANS4>2.0.ZU;2-7
Abstract
A novel sugar in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa has been identified. The sugar was liberated from the lipopolys accharide when hydrolyzed in 10 M HCl at 90-degrees-C for 15 min. The sugar was purified and identified as 4-amino-4,6-dideoxy-2-O-methylman nose (2-O-methylperosamine). Since it was found only in the lipopolysa ccharide of Vibrio cholerae O1 serotype Ogawa, it seems that the sugar is one of the specific constituents determining Ogawa serotype specif icity.