ANALYSIS OF MHC-PRESENTED PEPTIDES - APPLICATIONS IN AUTOIMMUNITY ANDVACCINE DEVELOPMENT

Authors
CHICZ RM URBAN RG
Citation
Rm. Chicz et Rg. Urban, ANALYSIS OF MHC-PRESENTED PEPTIDES - APPLICATIONS IN AUTOIMMUNITY ANDVACCINE DEVELOPMENT, Immunology today, 15(4), 1994, pp. 155-160
Citations number
45
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
15
Issue
4
Year of publication
1994
Pages
155 - 160
Database
ISI
SICI code
0167-5699(1994)15:4<155:AOMP-A>2.0.ZU;2-L
Abstract
T cells recognize antigenic peptides presented on the cell surface by major histocompatibility complex (MHC) molecules. Here, Roman Chicz an d Robert Urban describe the features of peptides bound to MHC molecule s and the mechanism by which these surface proteins bind diverse pepti de ligands with high affinity. In addition, they discuss the applicati on of new technologies to the identification of MHC-associated peptide s.