Bw. Lytle et al., INFLUENCE OF ARTERIAL CORONARY-BYPASS GRAFTS ON THE MORTALITY IN CORONARY REOPERATIONS, Journal of thoracic and cardiovascular surgery, 107(3), 1994, pp. 675-683
From 1988 through 1991, 1663 patients underwent a first reoperation fo
r isolated coronary bypass grafting with 62 (3.7%) in-hospital deaths.
At the primary operation, 575 patients had received at least one inte
rnal thoracic artery graft and 489 patients had at least one patent in
ternal thoracic artery graft present at the time of reoperation. At re
operation, 1014 patients received at least one internal thoracic arter
y graft, 10 received an inferior epigastric graft, and 37 received a g
astroepiploic graft. Of 489 patients with patent internal thoracic art
ery grafts at reoperation, the internal thoracic artery was damaged in
17 (3.5%); of 428 patients with a patent internal thoracic artery gra
ft to the left anterior descending coronary artery, 14 (3.3%) had graf
t damage necessitating regrafting. All patients with damaged internal
thoracic arterys survived. Multivariate testing of variables for their
association with in-hospital mortality identified no internal thoraci
c artery graft at either primary surgery or reoperation (p < 0.0001),
a history of congestive heart failure (p < 0.0001), advancing age (p =
0.018), female gender (p = 0.029), and emergency operation (p = 0.01)
as factors linked to increased risk. Left ventricular function, left
main stenosis, extent of native coronary atherosclerosis, and the inte
rval between operations did not influence mortality. Furthermore, the
presence of an atherosclerotic vein graft to the left anterior descend
ing coronary artery a factor shown to increase in-hospital risk in pre
vious studies did not increase risk during these years. We attribute t
he observation that patent internal thoracic artery and atheroscleroti
c vein grafts do not appear to be factors specifically increasing the
risk of reoperation to the use of retrograde cardioplegic solution and
increased surgical experience. The use of internal thoracic artery gr
afts at a primary operation does not increase the risk of a reoperatio
n, and the use of internal thoracic artery grafts at reoperation does
not increase in-hospital morbidity or mortality.