Sd. Hillis et al., RISK-FACTORS FOR RECURRENT CHLAMYDIA-TRACHOMATIS INFECTIONS IN WOMEN, American journal of obstetrics and gynecology, 170(3), 1994, pp. 801-806
OBJECTIVE: We evaluated risk factors for recurrent Chlamydia trachomat
is infections in women. STUDY DESIGN: We used a retrospective cohort d
esign to examine predictors of recurrent infection in the 38,866 femal
e residents of Wisconsin whose first reported C. trachomatis infection
occurred between 1985 and 1989. RESULTS: Young age at first reported
infection was the strongest predictor of recurrent C. trachomatis infe
ction, after adjustment for covariates. Adolescents < 15 years old had
an eightfold increased risk, those 15 to 19 years old had a fivefold
increased risk, and women 20 to 29 years old had a twofold increased r
isk of recurrent C. trachomatis infection, compared wit; that among wo
men 30 to 44 years old. In 54% of those aged < 15 at initial infection
and 30% of those aged 15 to 19, recurrence developed. Other character
istics associated with recurrence included black race, residence in Mi
lwaukee County, coinfection with gonorrhea, and past sexually transmit
ted diseases; receiving care in a family-planning clinic appeared prot
ective. CONCLUSIONS: Implementation of strategies to reduce the marked
ly elevated risk of recurrent chlamydia infections is urgently needed
in female adolescents.