T. Rauen et Bi. Kanner, LOCALIZATION OF THE GLUTAMATE TRANSPORTER GLT-1 IN RAT AND MACAQUE MONKEY RETINAE, Neuroscience letters, 169(1-2), 1994, pp. 137-140
Antibodies directed against a glutamate transporter (GLT-1) purified f
rom rat brain were applied to cryostat sections of rat and macaque mon
key retinae. In the brain, GLT-1 expression is found mainly in astrocy
tes, and therefore it has been suggested that GLT-1 may be a glutamate
transporter specific to glial cells. However, in the rat retina, cone
s and two distinct cone bipolar cell types were strongly immunoreactiv
e. In the monkey retina, flat midget bipolars and one diffuse bipolar
cell type (DB2)), were found to be labelled. Muller cells or astrocyte
s, the neuroglial cells of rat and monkey retinae, were not GLT-1-immu
noreactive.