Da. Hood et Rl. Terjung, ENDURANCE TRAINING ALTERS ALANINE AND GLUTAMINE RELEASE FROM MUSCLE DURING CONTRACTIONS, FEBS letters, 340(3), 1994, pp. 287-290
The release of alanine and glutamine from perfused muscle of trained a
nd control animals was investigated. Release rates did not differ betw
een trained and control muscle at rest. During contractions in trained
muscle, alanine release was higher than at rest, while glutamine rele
ase was transiently increased. Phenylalanine release did not differ be
tween trained and control muscle, implying that protein degradation wa
s not increased in trained muscle. The muscle cellular adaptations to
training include a selective modification of amino acid output, which
could potentially influence gluconeogenic flux and alter muscle ammoni
a levels during contractions.