LIPOXYGENASE INHIBITORS .3. SYNTHESIS OF TETRAHYDROBENZAZEPINONE PHENYLHYDRAZONES

Authors
BUGE A LOCKE C KOHLER T NUHN P
Citation
A. Buge et al., LIPOXYGENASE INHIBITORS .3. SYNTHESIS OF TETRAHYDROBENZAZEPINONE PHENYLHYDRAZONES, Archiv der pharmazie, 327(2), 1994, pp. 99-103
Citations number
20
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
327
Issue
2
Year of publication
1994
Pages
99 - 103
Database
ISI
SICI code
0365-6233(1994)327:2<99:LI.SOT>2.0.ZU;2-E
Abstract
Tetrahydro-2H-benz[b]azepin-2-ones as starting substances are synthesi zed by Beckmann rearrangement or Schmidt reaction. The tetrahydro-benz azepinones are transformed into the thiones, thiolactim ethers and phe nylhydrazones. The compounds are tested as inhibitors of soja lipoxy-g enase.