Ba. Carroll, SEGMENTAL STENOSIS OF THE RENAL-ARTERY - PATTERN-RECOGNITION OF TARDUS AND PARVUS ABNORMALITIES WITH DUPLEX SONOGRAPHY, Investigative radiology, 29(3), 1994, pp. 390-391
Segmental renal artery branches were evaluated using color Doppler ima
ging and pulsed Doppler spectral analysis in a prospective fashion in
56 patients with suspected peripheral vascular disease who underwent s
ubsequent angiography. Thirty-four of the 56 patients were hypertensiv
e. Pulsed Doppler waveform analysis was performed to assess accelerati
on time, acceleration index, and loss of the normal early systolic pea
k (ESP). These three parameters were compared with the findings obtain
ed on subsequent angiograms to assess their efficacy for detecting gre
ater than or equal to 60% renal arterial stenosis (RAS). Thirty-two ki
dneys in 26 patients demonstrated angiographic evidence of greater tha
n or equal to 60% stenosis. Three patients had multiple renal arteries
, none of which were stenotic. No segmental arteries demonstrated sten
osis. Evaluation of ESP proved to be the best of the three parameters
evaluated for identifying greater than or equal to 60% stenosis. Loss
of the ESP identified RAS with 95% sensitivity, 97% specificity, a 92%
positive predictive value, a 98% negative predictive value, and 96% o
verall accuracy. Two categories of waveform abnormalities, one moderat
e and one more severe, were associated with a loss of ESP. Detection o
f tardus and parvus abnormalities in the segmental renal arteries is a
dvocated as an indirect means of diagnosing renal artery stenosis. Pat
tern recognition of loss of the normal ESP had better sensitivity and
specificity than acceleration time or acceleration index for diagnosin
g greater than or equal to 60% RAS. The authors were unable to disting
uish between renal artery occlusion with collateral arterial supply to
the kidneys and severe main renal artery stenosis. However, they were
successful in all kidneys in whom a patent renal artery was found at
angiography.