DIAGNOSIS AND TREATMENT OF ANEMIA IN PATI ENTS EXPOSED TO AROMATIC ORGANIC-SOLVENTS

171 iron-deficient painters and 20 subjects with chronic intoxication with aromatic hydrocarbons were studied in a large aircraft constructi on factory. After correlative analysis of iron metabolism, ferritin, e rythrocytes, diameter and perimeter of reticulocytes, length of servic e three types of iron-deficiency were identified: typical, with eviden t toxicity, with a high risk of toxic damage. An important role of lip id peroxidation activity and toxic erythrocytomembranopathy for pathom orphosis of iron deficiency anemia and progress of toxical anemia is d emonstrated. A differential approach to treatment of different anemia variants was used. The treatment included membranoprotectors (alpha-to copherol, essentiale, lypostabil) and unspecific detoxication (SUMS-en terosorbent, unitiol).