Ha. Dyadyk et al., THE SIGNIFICANCE OF DISCLOSURE OF THE NUC LEOLUS ORGANIZERS FOR DIAGNOSIS OF HUMAN BENIGN AND MALIGNANT-TUMORS, Eksperimental'naa onkologia, 15(6), 1993, pp. 8-12
The review presents data on the structure and functions of the nucleol
us organizer region and relations of the organizer with cell proteins.
A particular role of some non-histone acidic proteins and RNA-polymer
ase I in disclosure of the nucleolus organizer region by means of silv
er nitrate is described. The data presented demonstrate the significan
ce of the nucleolus organizer region for determination of the tumour g
rowth peculiarities.