THE TEST OF NATURAL LEUKOCYTE EMIGRATION INHIBITION IN-VIVO WITH ASPIRIN AND ANALGIN IN SPECIFIC DIAGNOSIS OF THE ASTHMATIC TRIAD

Asthmatic triad (AT) is a clinical syndrome incorporating bronchial as thma (BA), recurrent nasal and sinus polyps, intolerance of aspirin, d erivatives of pirasolone and other nonsteroid antiinflammatory drugs. Specific diagnosis of aspirin and analgin intolerance in patients with AT was made using tile test of natural leukocyte emigration inhibitio n in vivo in the oral cavity. Tile test was performed in 22 patients w ith AT and 13 patients with BA with pollenosis without aspirin and ana lgin intolerance. In all the patients the test provided positive resul ts, in control patients these were negative. High significance, safety and simplicity of the test made it applicable for specific diagnosis of AT in allergological and pulmonological departments.