Changes in blood lipids were assessed in the course of 4 years in 29 p
atients with cholesterol (CS) levels at least 300 mg/dl (hyperlipidemi
a). Of these, 20 received mevakor, 9 were controls. Taking mevacor in
a dose 20-40 mg/day for 6 months reduced CS in the study group by 20%
and by 10% more within the next 6 months. CS in controls changed unnot
iceably. Lowering of the dose to 10-20 mg/day or mevacor discontinuati
on at the moment CS fell to 250 mg/dl or greater did not entail a reri
se of total blood CS within subsequent 4-6 months.