A. Halabe et al., HYPOPARATHYROIDISM - A LONG-TERM FOLLOW-UP EXPERIENCE WITH 1-ALPHA-VITAMIN-D-3 THERAPY, Clinical endocrinology, 40(3), 1994, pp. 303-307
OBJECTIVE Previous studies have suggested that alpha-D-3 therapy can c
ause deterioration in renal function. We have, therefore, examined the
long-term effect of 1 alpha-hydroxyvitamin D-3 (alpha-D-3) administra
tion upon renal function in hypoparathyroid patients. DESIGN This is a
prospective long-term follow-up study of alpha-D-3 administration on
hypoparathyroid patients at a mean daily dose of 1 mu g (range 0.5-2.5
mu g) during a total of 2040 patient-months.