GRANULOMA AFTER AUGMENTATION OF THE EYELIDS WITH LIQUID SILICONE - ANELECTRON-MICROSCOPIC STUDY

Granuloma after liquid silicone augmentation of the upper eyelids was studied by light and electron microscopy and energy dispersive x-ray a nalysis. Light microscopy showed proliferation of collagen fibers and many phagocytic macrophages with vacuoles. Electron microscopy showed many vacuoles in phagocytic macrophages, fragmentary myofibrils, and p roliferation of collagen fibers. Vacuoles in phagocytic macrophages co ntained silicone that was demonstrated by energy dispersive x-ray anal ysis. The present case suggests that liquid silicone injection in the eyelid can induce degeneration of the orbicularis oculi muscle in addi tion to granuloma formation.