NOVEL 3-BETA-METHOXYSTEROIDS FROM THE SENEGALESE SPONGE MICROSCLERODERMA-SPIROPHORA

Authors
COSTANTINO V FATTORUSSO E MANGONI A AKNIN M GAYDOU EM
Citation
V. Costantino et al., NOVEL 3-BETA-METHOXYSTEROIDS FROM THE SENEGALESE SPONGE MICROSCLERODERMA-SPIROPHORA, Steroids, 59(3), 1994, pp. 181-184
Citations number
8
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Steroids → ACNP
ISSN journal
0039128X
Volume
59
Issue
3
Year of publication
1994
Pages
181 - 184
Database
ISI
SICI code
0039-128X(1994)59:3<181:N3FTSS>2.0.ZU;2-W
Abstract
The Senegalese sponge Microscleroderma spirophora has been found to pr oduce exclusively very unusual 3 beta-methoxysteroids in place of the common 3 beta-hydroxysteroids. Six different methoxysteroids (three of which are novel compounds) have been isolated and identified by spect roscopic means (MS, IR H-1 and C-13 NMR), and their taxonomic signific ance discussed. A new method for the determination of the configuratio n at C-24 in satuiated 24-ethyl side chains is also proposed.